Research

RESEARCH
Our research group at the Department of Pharmaceutical Science and Technology, ICT is actively involved in design and development of lipid and colloidal drug delivery systems for various routes like oral, topical, transdermal, nasal and parenteral. We investigate, develop and optimize formulation design for drugs using delivery systems that include microemulsions, nanoemulsions, polymeric nanoparticles, solid lipid nanoparticles (SLNs), self microemulsifying drug delivery systems (SMEDDs), self microemulsifying tablets (SMETs) and liquid crystalline systems for a wide variety of ailments which include cancer, alzheimers disease and tropical infectious diseases like malaria, tuberculosis and brucellosis. We believe these delivery systems offer multifarious advantages over conventional dosage forms and show rapid onset of action, patient compliance, and less incidence of toxicological side effects. Many pre-scanned, potential actives including antimicrobials, antihistaminics, cardiovascular agents, antineoplastics, anti-inflammatory drugs, peptides, immunomodulators covering Biopharmaceutical classification categories of II and IV have been successfully formulated in our drug delivery laboratory.

Our group additionally investigates various drug solubilization and incorporation techniques that employ  novel carrier mediated systems, exploration of potential of indigenous excipients in pharmaceuticals and cosmeceuticals, and development of target organ oriented dosage forms.

A few other interests of our lab include diagnostics and fabrication of devices for intravascular and intrauterine purposes.

OUR RESEARCH AREAS

RESEARCH GRANTS:

No.

Title

Funding agency

1.        

Nanovaccine for Brucellosis using Green Technology

Grand Challenges Explorations Grants Round 11, Bill & Melinda Gates Foundation, USA

2.      

Hot Melt Extrusion Assisted Solid Dispersions for Oral Bioenhancement of Poorly Bioavailable Drugs under collaborative project ‘Process analytics enabled green technologies for processing of poorly soluble drugs’

UKIERI (UK-India Education and Research Initiative) funded by British council

3.

Process Engineering For Fabrication of Micro/ Nano Particles

 

All India Council of Technical Education (AICTE)

4.

Rectal Microbicidal Nanotherapeutics for HIV/ AIDS

Department of Biotechnology (DBT)- Indian Council of Medical Research (ICMR)

5.

Nanotechnology-based Diagnostic Module for Detection of Brucellosis

Indian Council of Medical Research (ICMR)

6.

Therapeutic approaches using controlled transdermal delivery to treat neurodegenerative diseases in aging populations

Department of Science and Technology (DST)

7.

Extraction and isolation of seabuckthorn actives for developing nanocarrier based cosmeceuticals

Department of Biotechnology (DBT)

8.

Application of Supercritical fluid extraction technology in the production of lectin mediated colon targeting micro/nano-particles.

Department of Biotechnology (DBT)

9.

Nanotherapeutics with Lipidic nanoparticles for the treatment of malaria

Department of Biotechnology (DBT)

10.

Development and evaluation of novel brain targeted nasal drug delivery system

Board of Radiation and Nuclear Sciences (BRNS)

11.

Development of novel polymer based drug delivery system

All India Council of Technical Education (AICTE)

12.

Microemulsions as vehicles for transdermal use

University Grants Commission (UGC)

13.

Radiation effects on the controlled release of ophthalmic drug delivery systems

Department of Atomic Energy (DAE) as Co-PI

14.

Development of anti-arthritic/anti-inflammatory transdermal therapeutics systems

University Grants Commission (UGC)

Departmental Grants

1.        

Formulation of tea tree oil

UDCT Golden Jubilee Research Fund Endowment

2.        

Development of microemulsion based multipurpose anti-acne gels

UDCT Golden Jubilee Research Fund Endowment

3.        

Evaluation of antacid formulations

UDCT  Alumni

4.        

Indigenous wax: anti-aging potential

UDCT Golden Jubilee Research Fund Endowment

5.        

Use of indigenous excipients for a new drug delivery system

UDCT Golden Jubilee Research Fund Endowment